Once Saved Always Saved (or perhaps more popularly called Perseverance of the Saints, but I like the baptist terminology, even though it's perhaps more misleading) falls out naturally from the concept of radical corruption (or total depravity) and predestination. If both can be shown to be Biblical and true then the conclusion is a given.
Since man is incapable of saving himself it must be God alone who saves us. 1 Cor2:14, Romans 3:10-11.
God never changes, not His mind, not His person, not ever. Numbers 23:19, 1 Sam 15:29
Therefore, if we didn't have the power to say no to Him in the first place, we cannot at a later time say no.
It's that straightforward.
If God is immutable, and man is weak, then once saved always saved is the only option.
Or, if it can be shown that God is in sovereign control over every aspect of our lives, including our coming to Him in faith, then He has obviously determined to save us, and will certainly save us, and once saved always saved must be true. If God gives us the Spirit who regenerates us, justifies us, and sanctifies us, 1 Cor 6:11 if He has adopted us as His very own Rom 8:15, if He has made it all possible and sealed us up with the Holy Spirit Eph 4:30 then salvation belongs to God alone Jonah 2:9, Psalms 3:8.
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